Patricia Mendonca

New Pharmacy Building – Phase II - room G134N

Wednesday: 2:30pm - 4:00pm or online (via Zoom)

BSC 2085L  •  Anatomy and Physiology I Lab
BSC 2086L  •  Anatomy and Physiology II Lab
ZOO 3603L  •  Developmental Anatomy Lab
ZOO 3603  •  Developmental Anatomy Lecture

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I am an Assistant Professor in the Department of Biological Sciences and work as a Research Analyst for the College of Pharmacy and Pharmaceutical Science. My research is focused on the effect of natural compounds in triple-negative breast cancer. In the lab I have been training Master and Ph.D. students.

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• Triple-Negative Breast Cancer and Health Disparities
• Natural Products, Phytochemicals, and Flavonoids in Disease Prevention and Therapy
• Antioxidant Pathways and Neurodegenerative Disease Mechanisms

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• Assistant Professor • 2021 - Present
  College of Science and Technology - Department of Biology, Florida A&M University, Tallahassee, FL
• Research Analyst RCMI • 2021 - Present
  College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL
• Research Associate • 2018 - 2021
  College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL
• O.P.S. Research Associate • 2017 - 2018
  College of Pharmacy and Pharmaceutical Sciences, RCMI Molecular Genetic Core, Florida A&M University, Tallahassee, FL
• Research Assistant •  2013 - 2017
  College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL

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• 32 peer-reviewed publications in high-impact journals
• 2 book chapter contributions
• 52 scientific presentations at national and international conferences

Most Recent Publications:

1. Hilliard AL, Russell TD, Mendonca P, Soliman KFA. Targeting the Tumor Immune Microenvironment in Triple-Negative Breast Cancer: The Promise of Polyphenols. Cancers (Basel). 2025 Aug 27;17(17):2794. doi: 10.3390/cancers17172794. PMID: 40940890; PMCID: PMC12427469.
2. Mishra SD, Mendonca P, Kaur S, Soliman KFA. Silibinin Anticancer Effects Through the Modulation of the Tumor Immune Microenvironment in Triple-Negative Breast Cancer. Int J Mol Sci. 2025 Jun 28;26(13):6265. doi: 10.3390/ijms26136265. PMID: 40650040; PMCID: PMC12250461.
3. Patricia Mendonca, Sukhmandeep Kaur, Bhonesa Kirpal, Karam FA Soliman. Cardamonin anticancer effects through the modulation of the tumor immune microenvironment in triple-negative breast cancer cells. Am J Cancer Res. 2024 Dec 15;14(12):5644-5664. doi: 10.62347/ANXS3815. PMID: 39803666; PMCID: PMC11711538.
4. Kaur S, Mendonca P, Soliman KFA. The Anticancer Effects and Therapeutic Potential of Kaempferol in Triple-Negative Breast Cancer. Nutrients. 2024 Jul 23;16(15):2392. doi: 10.3390/nu16152392. PMID: 39125273; PMCID: PMC11314279.
5. Ahmed, Shade’ A., Patricia Mendonca, Samia S. Messeha, Ebenezer T. Oriaku, and Karam F. A. Soliman. The Anticancer Effects of Marine Carotenoid Fucoxanthin through Phosphatidylinositol 3-Kinase (PI3K)-AKT Signaling on Triple-Negative Breast Cancer Cells. 2023 Dec 21;29(1):61. https://doi: 10.3390/molecules29010061. PMID: 38202644; PMCID: PMC10779870.
6. Ahmed, Shade’ A., Patricia Mendonca, Samia S. Messeha, and Karam F. A. Soliman. Anticancer Effects of Fucoxanthin through Cell Cycle Arrest, Apoptosis Induction, and Angiogenesis Inhibition in Triple-Negative Breast Cancer Cells. Molecules 2023, 28, no. 18: 6536. https://doi.org/10.3390/molecules28186536.
7. Evans, J.A.; Mendonca, P.; Soliman, K.F.A. Involvement of Nrf2 Activation and NF-kB Pathway Inhibition in the Antioxidant and Anti-Inflammatory Effects of Hesperetin in Activated BV-2 Microglial Cells. Brain Sci. 2023, 13, 1144. https://doi.org/10.3390/brainsci13081144.
8. Barber, K.; Mendonca, P.; Evans, J.; Soliman, K.F.A. Antioxidant and Anti-inflammatory Mechanisms of Cardamonin through Nrf2 Activation and NF-kB Suppression in LPS-Activated BV-2 Microglial Cells. Int. J. Mol. Sci. 2023, 24, 10872. https://doi.org/10.3390/ijms241310872.
9. Konan J.W. Kanga, Lambert H.B. Kanga, Patricia Mendonca, Karam F.A. Soliman, Dominique T. Ferguson, Sarah L. Reed, and Selina Darling-Reed. Attenuative Effect of Diallyl Trisulfide on Caspase Activity in TNF-α-Induced MDA-MB-231 and MDA-MB-468 Triple Negative Breast Cancer Cells. Anticancer Res. 2023 Jun;43(6):2393-2405. doi: 10.21873/anticanres.16407. PMID: 37247921.

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Prestigious honors, including:

• The 2022 George K. Michalopoulos Junior Faculty Scholar Award from the American Society for Investigative Pathology (ASIP)
• The 2023 Sidney A. McNairy Award for Inclusive Excellence at the Research Centers in Minority Institutions (RCMI) Conference

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• LinkedIn